Antimicrobial susceptibility pattern of Burkholderia cepacia isolates from patients with malignancy

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Antimicrobial susceptibility and synergy studies of Burkholderia cepacia complex isolated from patients with cystic fibrosis.

Susceptibility (18 antimicrobial agents including high-dose tobramycin) and checkerboard synergy (23 combinations) studies were performed for 2,621 strains of Burkholderia cepacia complex isolated from 1,257 cystic fibrosis patients. Minocycline, meropenem, and ceftazidime were the most active, inhibiting 38%, 26%, and 23% of strains, respectively. Synergy was rarely noted (range, 1% to 15% of ...

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Biocide susceptibility of the Burkholderia cepacia complex.

OBJECTIVES The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated it to their taxonomy, antibiotic susceptibility and ability to form biofilms. M...

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ژورنال

عنوان ژورنال: Journal of Global Infectious Diseases

سال: 2014

ISSN: 0974-777X

DOI: 10.4103/0974-777x.132064